| Lane | Athlete | Team | Seed | Note |
|---|---|---|---|---|
| 1 | FROST, Julia | Ashley Ridge | 2:41.00 | |
| 2 | ABLES, Elliot | West Ashley | 2:43.63 | Patriot Invitational |
| 3 | CINNAMON, Lacie | Summerville | 2:46.82 | Dorchester County |
| 4 | REIDY, Violet | Fort Dorchester | NT | |
| 5 | HOLMES, Mae Louise | James Island | 2:54.20 | Charleston County School Distric |
| 6 | DAVIS, Alyssa | Fort Dorchester | 3:02.42 | Dorchester County JV/MS Champion |
| 7 | WILSON, Erin | Fort Dorchester | NT | |
| 8 | PRICE, Mia | Fort Dorchester | 3:02.89 | Patriot Invitational |
| 9 | GARNETT, Nancy | Stall | 3:07.58 | Bob Jenkins Coaches Classic Trac |
| 10 | CLINE, Ada | West Ashley | 3:08.73 | Charleston County School Distric |
| 11 | TONEY, Kalissa | Stall | 3:13.24 | Bob Jenkins Coaches Classic Trac |
| Lane | Athlete | Team | Seed | Note |
|---|---|---|---|---|
| 1 | BELK, Avery | James Island | 2:18.28 | Azalea/Zaxby's Invitational |
| 2 | LARUE, Alexandra | James Island | 2:24.12 | Tri County Meet of Champions |
| 3 | TAYLOR, Alice | James Island | 2:24.16 | Charleston County School Distric |
| 4 | RAIFORD, Katelyn | Summerville | 2:29.48 | Cane Bay Track and Field Invitat |
| 5 | GRIFFITH, Kendall | Summerville | 2:30.01 | All American Track Classic |
| 6 | EMSLIE, Eloise | West Ashley | 2:36.28 | Charleston County School Distric |
| 7 | GORIN, Aubrey | Summerville | 2:36.46 | Tri County Meet of Champions |
| 8 | PRIEST, Carson | Ashley Ridge | 2:37.45 | |
| 9 | SACOR, Lyby | Ashley Ridge | 2:38.75 | |
| 10 | UNDERWOOD, Emily | Ashley Ridge | 2:40.00 | |
| 11 | KERR, Marina | West Ashley | 2:40.22 | Charleston County School Distric |