| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 1 | Chesterton | A | Resto | Throw | Vanderwoude | Powell | 3:40.00 | |
| 2 | South Bend Adams | A | Lemay | Anderson | Gutierrez | Johnson | 3:38.00 | |
| 3 | LaPorte | A | Clay | Pham | Hunt | Long | 3:35.29 | Trine HSR Qualifier #3 |
| 4 | South Bend Riley | A | Nabieu | Nabieu | Chibambo | 3:37.00 | ||
| 5 | Lakeland | A | Hostetler | Lawrence | Troyer | Schiffli | 3:39.04 | 2022 Goshen Relays - Boys Class B |
| 6 | Northridge | A | Estep | Mathias | Mann | 3:40.00 |
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 1 | Chesterton | B | Raffin | Palm | Handley | Woods | 3:50.00 | |
| 2 | Elkhart | A | Huckleberry | Newson | Leonard | Ryall | 3:43.59 | 2022 Goshen Relays - Boys Class A |
| 3 | South Bend St. Joseph | A | Miller | Sparke | Sparks | Imanene | 3:42.00 | |
| 4 | South Bend Riley | B | Witz | Pflugner | Pryor | Conley | 3:42.68 | 2022 Goshen Relays - Boys Class A |
| 5 | Huntington North | A | Plemons | Wagner | Voght | Blair | 3:45.00 | |
| 6 | South Bend St. Joseph | B | Risk | Finfrock | Dampeer | Serrano | 3:50.00 |
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 1 | Huntington North | B | Christiansen | Oswald | Brown | Bordeaux | 4:10.00 | |
| 2 | Fairfield | A | Henry | Miller | Herschberger | Garcia | 4:00.00 | |
| 3 | Lakeland | B | Hofer | Colon | Naylor | Larimer | 3:55.00 | |
| 4 | Angola | A | Morvilius | Smith | Weiss | Meyer | 3:55.00 | |
| 5 | Plymouth | A | Druzbicki | Graham | Mackey | Oleary | 4:05.00 | |
| 6 | Angola | B | Carminati | Heavin | Cooke | Soulliere | 4:10.00 |
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 2 | Trinity (Greenlawn) | A | Fletcher | Seachris | Mustillo | Roeber | 4:18.38 | 2022 NWI Championships |
| 3 | Elkhart | B | Hausbach | Gilbert | Grolich | Asa | 4:10.23 | |
| 4 | Fairfield | B | Geiger | Cripe | Metzger | Herr | 4:12.00 |