| Lane | Athlete | Team | Seed | Note |
|---|---|---|---|---|
| 1 | BONAMY, Mackenley | Boyd Anderson |
4:42.41 | Sam Burley Hall of Fame Invitational |
| 2 | JEOBOHAM, Bradford | Boyd Anderson |
4:51.72 | Coral Springs Invitational *SANCTIONED* |
| 3 | GALINDO, Fernando | Northeast (OP) |
5:00.02 | |
| 4 | PERICLES, Mykerson | Northeast (OP) |
5:00.10 | |
| 5 | BERTA, Magnus | Coral Springs |
5:13.40 | FHSAA 4A District 13 |
| 6 | BIENAIME, Gael | Northeast (OP) |
5:20.23 | |
| 7 | RANDOLPH, Richard | Hallandale |
5:45.00 | |
| 8 | BANKOLE, Toluwanimi | Chaminade-Madonna |
6:16.16 | FHSAA 1A District 15 |
| 9 | CLINE, Tyler | Coral Springs |
NT | |
| 10 | DESJARDINS, Terence | Chaminade-Madonna |
NT | |
| 11 | MARCELUS, Marvens | Coral Springs |
NT |