| Lane | Athlete | Team | Seed | Note |
|---|---|---|---|---|
| 1 | WHITE, Leah | Eudora | 13.05 | |
| 2 | MILES, Rori | Bennington | 13.00 | |
| 3 | AFONJA, Fisayo | Baldwin | 12.93 | DeSoto Invite |
| 4 | LUEHRS, Lacy | Cheney | 12.69 | Cheney Vernon Ferguson Invitational 2021 |
| 5 | AMEKPORFOR, Maddi | Andover Central | 12.91 | |
| 6 | SCHWARTZ, Sarah | Hutchinson | 12.95 | Valley Center Varsity Track Invitational |
| 7 | WRIGHT, Amy | Cheney | 13.04 | Cheney Vernon Ferguson Invitational 2021 |
| 8 | MCGRAW, Breaisha | Hutchinson | 13.10 |
| Lane | Athlete | Team | Seed | Note |
|---|---|---|---|---|
| 1 | YODER, Caryn | Hesston | 12.63 | James Thomas Invitational 2019 |
| 2 | PATTISON, Maya | Eudora | 12.60 | |
| 3 | JACKSON, Serenity | Wichita-South | 12.22 | 6A Regionals 2021 |
| 4 | HARRIS, Lillian | Wichita-Kapaun-Mt Carmel | 12.19 | 5A Regional %238 |
| 5 | HAMMOND, Brooke | Garden Plain | 12.20 | Cheney Vernon Ferguson Invitational 2021 |
| 6 | SPARKS, Tabitha | Bethany | 12.50 | |
| 7 | OBLINGER, Trinity | Wichita-Kapaun-Mt Carmel | 12.61 | 5A Regional %238 |
| 8 | FRIESEN, Emily | Hesston | 12.67 | Shocker Pre-State Challenge |