| Lane | # | Athlete | Team | Seed |
|---|---|---|---|---|
| 1 | 196 | Colby Wines | Chapman | 4:52.02 |
| 2 | 227 | Josue Garcia | Laurens | 4:52.14 |
| 3 | 215 | Maddox Bucher | Greer | 4:54.06 |
| 4 | 222 | Mason Dill | Landrum | 4:59.57 |
| 5 | 184 | John Gunter | Carolina Homeschool | 5:00.00 |
| 6 | 244 | Nathan Moseley | Spartanburg | 5:03.78 |
| 7 | 228 | Cody Patterson | Laurens | 5:05.02 |
| 8 | 225 | Fate Hall | Landrum | 5:07.00 |
| 9 | 182 | Lakota Woods | Byrnes | 5:14.88 |
| 10 | 239 | Micah Ganson | Northwestern | 5:15.73 |
| 11 | 176 | Brice Odom | Broome | 5:25.00 |
| 12 | 209 | Jackson Calvert | Gaffney | 5:25.64 |
| 13 | 167 | Jayden Adams | Boiling Springs | 5:29.97 |
| 14 | 171 | Luke Hurley | Boiling Springs | 5:38.44 |
| 15 | 175 | Bobby Nichols | Broome | 5:49.00 |
| 16 | 212 | Brayden Hughes | Gaffney | 6:05.72 |
| Lane | # | Athlete | Team | Seed |
|---|---|---|---|---|
| 1 | 208 | Devon Sibley | Fort Mill | 4:24.36 |
| 2 | 201 | Elias Workman | Dorman | 4:28.52 |
| 3 | 232 | Alan Dayrit | Nation Ford | 4:34.75 |
| 4 | 205 | Liam Eident | Fort Mill | 4:36.12 |
| 5 | 231 | Alexander Bentley | Nation Ford | 4:38.92 |
| 6 | 191 | Scott Keen | Catawba Ridge HS | 4:41.27 |
| 7 | 197 | Grayson Bryant | Dorman | 4:42.09 |
| 8 | 220 | Jackson Tuck | Greer Middle College Charter | 4:44.27 |
| 9 | 179 | Jon Cummings | Byrnes | 4:45.10 |
| 10 | 193 | Jack Myatt | Catawba Ridge HS | 4:45.10 |
| 11 | 241 | Benjamin Notarangelo | Northwestern | 4:46.04 |
| 12 | 187 | James Pepper | Carolina Homeschool | 4:47.69 |
| 13 | 219 | Beason Tuck | Greer Middle College Charter | 4:49.96 |
| 14 | 243 | Lars Harris | Spartanburg | 4:51.96 |