| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 2 | Nerinx Hall High School | A | Decker | Elgin | Andres | O'Gorman | 5:10.00 | Unverified: |
| 3 | Webster Groves High School | A | Lawless | Combs | Logan | Riefle | 4:55.29 | Unverified: |
| 4 | Parkway West High School | A | Phillips | Freed | Ivanova | Cauley | 5:00.00 | Unverified: Henle Holmes Invite |
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 2 | Ladue Horton Watkins High School | A | 4:50.00 | Unverified: | ||||
| 3 | Kirkwood High School | A | Person | Martz | Mitchell | MacLellan | DNS | Unverified: Corey Siebert Coed T&F Invitatio |
| 4 | Lindbergh High School | A | Bocquillon | Bocquillon | Zoeller | Banning | 4:45.02 | Verified |
| 5 | Mehlville High School | A | TROSKY | Kareem | Mathews | Wiszkon | DNS | Verified |
