| Lane | Athlete | Yr. | Team | Seed | Note |
|---|---|---|---|---|---|
| 3 | SUMNER, Preston | FR | Southern Illinois | NT | |
| 4 | MARSHALL, Marques | FR | Tennessee-Martin | 25.58 | Bellarmine Open (1/21/2022) |
| 5 | MASSIAH, Caleb | FR | Southern Illinois | NT |
| Lane | Athlete | Yr. | Team | Seed | Note |
|---|---|---|---|---|---|
| 2 | MARTINEZ, Marco | JR | McKendree | 24.92 | Dick Cochran Classic 2021 (4/23/2021) |
| 3 | BURRELL, Rahim | JR | Chicago State | 24.22 | Bob Harris Open (5/01/2021) |
| 4 | JONES, Joel | SO | Harding | 24.04 | Hendrix Invitational 2021 (3/14/2021) |
| 5 | SPELLS, Mychah | SO | Chicago State | 24.10 | GVSU Snowdown Showdown (2/04/2022) |
| 6 | GREAVES, Cole | Unattached | 24.50 | ||
| 7 | GRIFFIN, Henry | SO | Tennessee-Martin | 25.08 | Margaret Simmons Invite (3/25/2022) |
| Lane | Athlete | Yr. | Team | Seed | Note |
|---|---|---|---|---|---|
| 1 | BUTLER, James | FR | Southern Indiana | 23.98 | Margaret Simmons Invite (3/25/2022) |
| 2 | MANZI, Trace | SO | Southern Indiana | 23.53 | Margaret Simmons Invite (3/25/2022) |
| 3 | JACKSON, Stephon | SR | Chicago State | 23.45 | Blue Demon Holiday Invite (12/10/2021) |
| 4 | FORREST, Anthony | SO | SE Missouri | 23.10 | Ole Miss Classic (3/25/2022) |
| 6 | BROWN, Jibreel | SR | Lewis | 23.48 | Benedictine Eagle Tune-Up (4/30/2021) |
| 7 | MCKAY, Jayden | SO | Western Illinois | 23.95 | ESU Relays (3/24/2022) |
| 8 | SMITH, Jakai | JR | Chicago State | 23.98 | raw:23.91 2022 Western Athletic Conference Indoor T&F Championships (2/18/2022) |
| Lane | Athlete | Yr. | Team | Seed | Note |
|---|---|---|---|---|---|
| 1 | SKINNER, Kenyon'TA | JR | Western Illinois | 23.05 | The Summit League Indoor Track & Field Championships (2/25/2022) |
| 2 | HILL, Jamaric | SO | Harding | 22.96 | Rumble in the Jungle Invitational (1/21/2022) |
| 4 | HAMILTON, Zach | JR | Southern Indiana | 22.62 | Margaret Simmons Invite (3/25/2022) |
| 5 | SPELLS, Malachi | SO | Chicago State | 22.63 | WAC Outdoor Track and Field Championships (5/13/2021) |
| 6 | THOMPSON, Jamire | JR | Tennessee-Martin | 22.92 | OVC championship (5/13/2021) |
| 7 | PATTERSON, LaVell | SO | Chicago State | 22.96 | Blue Demon Holiday Invite (12/10/2021) |
| 8 | GARRETT, Terrico | SO | SE Missouri | 23.10 |
| Lane | Athlete | Yr. | Team | Seed | Note |
|---|---|---|---|---|---|
| 1 | MARTIN, Colby | SO | Tennessee-Martin | 22.49 | 2021 Joey Haines Invite (4/02/2021) |
| 2 | JONES, Jalen | SO | Chicago State | 22.29 | raw:22.22 2022 Western Athletic Conference Indoor T&F Championships (2/18/2022) |
| 3 | SCHWAB, Collin | SR | SE Missouri | 22.20 | 2021 Kentucky Invtational (4/30/2021) |
| 4 | CARROLL, Malachi | JR | McKendree | 21.85 | 2021 NJCAA Region XI Championships (5/01/2021) |
| 5 | JOHNSON, Jaden | JR | Southern Illinois | 21.94 | Clark Wood Invitational (4/23/2021) |
| 6 | SMITH, Davion | FR | Harding | 22.26 | Texas State Bobcat Invitational (3/24/2022) |
| 7 | RUTHERFORD, JP | SO | Harding | 22.46 | Rhodes 7-Way Meet (4/03/2021) |
| 8 | KEITH, Wesley | SO | Chicago State | 22.58 | WAC Outdoor Track and Field Championships (5/13/2021) |
| Lane | Athlete | Yr. | Team | Seed | Note |
|---|---|---|---|---|---|
| 1 | MCKENZIE, Ricordo | Chicago State | 21.75 | WAC Outdoor Track and Field Championships (5/13/2021) | |
| 2 | MCCARTHY, Conor | SR | SIU Edwardsville | 21.62 | OVC Indoor Track & Field Championships (2/23/2022) |
| 3 | BRETZ, Brandon | JR | SIU Edwardsville | 21.56 | Illinois State Invitational (4/30/2021) |
| 4 | KIRBY, Tad | SO | Harding | 21.41 | raw:21.34 WTAMU Last Chance (5/16/2021) |
| 5 | NERO, Jalen | SR | Unattached | 21.45 | |
| 6 | BUSH, Dakarai | SO | Harding | 21.61 | Texas State Bobcat Invitational (3/24/2022) |
| 7 | NUZZO, Robert | JR | SIU Edwardsville | 21.73 | Illinois State Invitational (4/30/2021) |
| 8 | EDWARD, Dasani | SO | Southern Illinois | NT |
