Section 1 of 2
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 2 | Webster Groves High School | A | Booth | Bias | Bronner | Logan | DNS | Unverified: |
| 3 | St. Louis University High School | A | Mayer | Seal | Mittendorf | Siemer | 3:55.56 | Unverified: |
| 4 | Mehlville High School | A | Ordaz | Pesselato | Silies | Evans | 4:05.31 | Verified |
Section 2 of 2
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 2 | Kirkwood High School | A | Kostos | Godwin | Wallace | Smith | 3:51.24 | Verified |
| 3 | Lafayette (Wildwood) High School | A | Retych | MANGELS | Keen | Webb | 3:40.29 | Unverified: |
| 4 | Ladue Horton Watkins High School | A | Lucas | Lee | Whitley | Hawthorne | 3:49.00 | Unverified: |
| 5 | Lindbergh High School | A | Deterding | Eaton | Westrich | Birk | 3:52.47 | Unverified: |
