Section 1 of 2
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed |
|---|---|---|---|---|---|---|---|
| 2 | Christian High School | A | Malone | Phillips | Kassebaum | Cunningham | 57.84 |
| 3 | Francis Howell North High School | A | Jones | Jones | Chance | Ausbury | 56.02 |
| 4 | Francis Howell Central High Scho | A | Mason | Ryan | Mabray | Anderson | NT |
| 5 | Bayless High School | A | Gladney | Owens | Brooks | Lormine | 55.56 |
| 6 | Mehlville High School | A | Baker | O'Shea | Silies | Abdijanovic | 57.09 |
Section 2 of 2
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed |
|---|---|---|---|---|---|---|---|
| 1 | St. Charles West High School | A | House | Myers | Shivers | Myers | 55.23 |
| 2 | Ft. Zumwalt West High School | A | White | Rowland | Moresi | Onuoha | 54.95 |
| 3 | Warrenton High School | A | DeHart | Schneider | Bostic | Besser | 53.92 |
| 4 | Timberland High School | A | Fletcher | Lightbody | Utley | Lewis | NT |
| 5 | Troy Buchanan High School | A | Hunolt | Robinson | Starkey | Crouch | 52.86 |
| 6 | Francis Howell High School | A | Schiermeier | Simmons | Nguyen | Jambois | 54.90 |
| 7 | Ft. Zumwalt North High School | A | Martin | Moody | Ramadan | Wolf | 55.20 |
| 8 | Northwest (Cedar Hill) High Scho | A | 55.40 |
