| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 2 | Northwest (Cedar Hill) High Scho | A | Judge | Frazier | Smith | Penberthy | 4:06.41 | Unverified: |
| 3 | Kirkwood High School | A | Earl | Larson | Sammler | Barry | DNS | Unverified: |
| 4 | Vianney High School | A | Loporto | Vahey | Turmelle | Boze | 4:01.86 | Verified |
| 5 | St. Louis University High School | A | 4:13.81 | Unverified: |