| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 3 | DeSoto High School | B | NT | Unverified: | ||||
| 4 | Ste. Genevieve High School | A | Huck | Greminger | Merklin | Clements | NT | Unverified: |
| 5 | Notre Dame (Cape Girardeau) High | B | Huck | Brotherton | Hennemann | Gamel | NT | Unverified: |
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 2 | Kelly High School | A | Barnhouse | Essner | Merrick | Ray | NT | Unverified: |
| 3 | Jackson High School | B | Golinski | GROSS | Pope | Shaw | 4:50.00 | Unverified: |
| 4 | Festus High School | B | 4:36.00 | Unverified: | ||||
| 5 | Saxony Lutheran High School | A | Yunck | Windeknecht | Thomason | Haley | NT | Unverified: |
| 6 | Scott City High School | A | 5:00.00 | Unverified: | ||||
| 7 | Rockwood Summit High School | B | Patton | Thier | Fountain | Shelton | NT | Unverified: |
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 1 | DeSoto High School | A | NT | Unverified: | ||||
| 2 | Central (Cape Girardeau) High Sc | A | Farrar | Moss | Snider | Caldwell | 4:24.00 | Unverified: |
| 3 | Notre Dame (Cape Girardeau) High | A | Eftink | Givens | Tatum | Carr | 4:20.00 | Unverified: |
| 4 | Dexter High School | A | Turnbo | Hale | Essner | Nea | 4:20.00 | Unverified: |
| 5 | Rockwood Summit High School | A | WINKLER | Shelton | Grimshaw | Jackson | 4:20.00 | Unverified: |
| 6 | Festus High School | A | Biehle | Perry | DeClue | Holmes | 4:24.00 | Unverified: |
| 7 | Central (Cape Girardeau) High Sc | B | Koehler | Dockery | Jackson | Mackins | 4:24.00 | Unverified: |
| 8 | Jackson High School | A | Metzger | Dunn | Metzger | Niedbalski | 4:36.00 | Unverified: |