Event Note:
| % | Championship | 46.68 | (Mackenzie Harsch,Rosie, Smith, Sasha Halfyard, Jamie Ashcroft | Alaska Anchorage | 2014 |
| # | GNAC | 46.19 | Simon Fraser | 2017 | |
| $ | McArthur Field | 46.82 | Seattle Pacific | 2015 |
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed | Note |
|---|---|---|---|---|---|---|---|---|
| 1 | Saint Martin's | A | Hamre, Grace | Whatley, Alexi | Hawthrone, Keirnan | Nickelson, Artresa | 49.42 | 49.42 Puget Sound Shotwell Invitational |
| 2 | MSU-Billings | A | Eastburn, Katie | Johnson, Michaela | Beckett, Brenna | Smiedala, Josey | 49.30 | 49.18 Montana Open |
| 3 | Seattle Pacific | A | Houk, Becca | Cai, Scout | Brannan, Kyra | Taylor, Lani | 47.38 | 47.38 Bryan Clay Invite |
| 4 | Simon Fraser | A | Kabia, Valda | Desch, Chantel | Pederson, Kira | Lucas, Katherine | 46.19 | 46.19 2017 Oxy Invitational %28College/University%29 |
| 5 | Alaska Anchorage | A | Ashcroft, Jamie | Cross, Mary Kathleen | Ries, Marie | Aniteye, Vanessa | 46.37 | 46.37 2017 Triton Invitational |
| 6 | Central Washington | A | Vongsaveng, Mariyah | Banfro, Tianna | Weems , Erykah | Garcia, Madison | DQ | 46.83 CWU Spike Arlt Inv |
| 7 | Western Washington | A | Allen, Macie | Bradley, Hannah | McLean, Kelsey | Smith, Savannah | 47.74 | 47.74 2017 Ralph Vernacchia Track %26 Field Meet |
| 8 | Northwest Nazarene | A | Bartlow, Rachel | Tubbs, Lexi | Gilmore, Carly | Deskins, Taylor | 49.34 | 49.34 CWU Spike Arlt Inv |